Advances in Neonatology: Evolution of Gastroschisis Management in a Developing Country
Keywords:
gastroschisis, mortality, structured protocolAbstract
Introduction: Gastroschisis presents a major challenge in resource-limited settings, particularly in Benin, where it was historically deemed 100% fatal until 2023. The implementation of a specific management protocol has led to a remarkable increase in survival rates.
Methods: prospective cross-sectional and observational study conducted at CHU-MEL in Cotonou from 1 year. A structured protocol was implemented
Results: Eight infants with gastroschisis were managed. Due to local constraints, the protocol could not be fully applied in all cases, particularly regarding antenatal diagnosis, general anesthesia, and parenteral nutrition. Seven cases presented with extensive perivisceritis, while one case involved vanishing gastroschisis. Half of the infants underwent primary closure. Three infants survived, corresponding to a survival rate of 37%, compared to the previous 0%. The primary causes of mortality were hypoglycemia and failure to recover from anesthesia.
Conclusion: This improvement demonstrates that progress is achievable with a structured approach. However, challenges remain, notably the lack of systematic antenatal diagnosis, anesthetic complications, and the unavailability of parenteral nutrition
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