Impact of Advanced Radiological Imaging on Oxidative Stress, Inflammation, and Recovery in Gynecologic Surgery.
Keywords:
Radiological imaging, gynecologic surgery, oxidative stress, inflammation, MRI, CT scan, postoperative recoveryAbstract
Background: Advanced radiological imaging has significantly improved the diagnosis and surgical planning of gynecologic diseases. Imaging modalities such as magnetic resonance imaging (MRI), computed tomography (CT), ultrasound, and intraoperative imaging technologies are increasingly used to guide minimally invasive gynecologic procedures. These techniques may influence surgical precision, perioperative stress responses, inflammatory processes, and postoperative recovery.
Objective: To evaluate the impact of advanced radiological imaging on oxidative stress, inflammatory responses, and postoperative recovery among patients undergoing gynecologic surgery.
Methods: A prospective observational study was conducted in the Department of Gynecology and Radiology of a tertiary care hospital from January 2024 to December 2024. A total of 120 women undergoing gynecologic surgery were enrolled and divided into two groups: Group A (n=60) underwent surgery planned using advanced radiological imaging techniques (MRI and CT-based planning), while Group B (n=60) underwent conventional imaging-based surgical planning (ultrasound only). Preoperative and postoperative biomarkers including malondialdehyde (MDA), superoxide dismutase (SOD), C-reactive protein (CRP), and interleukin-6 (IL-6) were measured. Postoperative recovery parameters including hospital stay, complication rates, and pain scores were recorded.
Results: Patients in Group A demonstrated significantly lower postoperative oxidative stress markers and inflammatory biomarkers compared with Group B. Mean postoperative CRP levels were significantly reduced in the advanced imaging group (18.3 ± 5.2 mg/L vs 29.6 ± 6.1 mg/L, p<0.001). Similarly, IL-6 levels were lower in Group A (42.5 ± 9.4 pg/ml vs 65.8 ± 10.1 pg/ml, p<0.001). Oxidative stress marker MDA levels were significantly reduced, while antioxidant enzyme SOD levels were higher in the advanced imaging group. Patients receiving advanced imaging planning also experienced shorter hospital stays and faster recovery.
Conclusion: Advanced radiological imaging plays an important role in improving surgical precision, reducing tissue injury,attenuating inflammatory responses, and promoting faster postoperative recovery in gynecologic surgery
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