Integrative Omics Approaches in Herbal Therapeutics: A Comprehensive Literature Review
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This literature review synthesizes current research on the integration of transcriptomics, proteomics, and genomics with herbal medicine, exploring their therapeutic potential, specific herb-disease interactions, and comparative impacts across different herbs. The review systematically analyzes 50 highly relevant studies from a pool of 460 papers, revealing that multi-omics approaches have transformed traditional herbal medicine research from empirical practice to data-driven science. Key findings demonstrate robust integration of transcriptomic, proteomic, and genomic data elucidating key signaling pathways and multi-target profiles underlying herbal efficacy, supported by advanced computational frameworks including machine learning and network algorithms. The review identifies significant methodological challenges in data standardization, experimental validation, and clinical translation while highlighting the transformative role of multi-omics in modernizing herbal medicine and advancing precision therapeutics
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