Management of Intestinal Strictures Post Conservative Treatment of Necrotizing Enterocolitis: The Long Term Outcome

Authors

  • Christoph Heinrich Houben Chinese University of Hong Kong Prince of Wales Hospital Shatin, N.T. Hong Kong
  • Kin Wai Chan Prince of Wales Hospital Department of Surgery
  • Wai Cheung Mou Prince of Wales Hospital Department of Surgery
  • Yuk Him Tam Prince of Wales Hospital Department of Surgery
  • Kim Hung Lee Prince of Wales Hospital Department of Surgery

DOI:

https://doi.org/10.21699/jns.v5i3.379

Keywords:

Necrotizing enterocolitis, Intestinal stricture, Primary anastomosis, Neurodevelopmental delay

Abstract

Objectives: Evaluating the long-term outcome of the surgical management for intestinal strictures developing after necrotizing enterocolitis (NEC).

Patients and methods: This is a retrospective study of all patients with an intestinal stricture after completion of conservative management for NEC. They were treated during the eight years period from 1st January 2008 to 31st December 2015.

Results: During the study period 67 infants had an operation for NEC, of which 55 had emergency surgery. The remaining twelve infants (6 males) had a stricture and were included in the study group. Their median gestational age was 35 (range 27-40) weeks and the median weight was 2180 (range 770 - 3290) g. The onset of NEC was seen at a median of 2 (range 1- 47) days. The median peak C-reactive protein (CRP) level was 73.1 (range 25.2 – 232) mg/dl. Isolated strictures were seen in 9 (75%) patients. Two-third of all strictures (n=15) were located in the colon. Surgery was done at a median of 5 (range 3 - 13) weeks after diagnosing NEC. Primary anastomosis was the procedure of choice; only one needed a temporary colostomy. This cohort had no mortality during a median follow up of 6.25 (range 0.5 - 7.6) years, whilst the overall death rate for NEC was 15 (22 %). Two fifth of the group developed a neurological / sensory impairment.

Conclusion: One fifth of the surgical workload for NEC is related to post-NEC strictures. Most strictures are located in the colonic region. In the long-term no mortality and no surgical co-morbidities were observed.

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Author Biography

Christoph Heinrich Houben, Chinese University of Hong Kong Prince of Wales Hospital Shatin, N.T. Hong Kong

ass Professor

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Published

2016-07-01

How to Cite

1.
Houben CH, Chan KW, Mou WC, Tam YH, Lee KH. Management of Intestinal Strictures Post Conservative Treatment of Necrotizing Enterocolitis: The Long Term Outcome. J Neonatal Surg [Internet]. 2016Jul.1 [cited 2021Feb.28];5(3):28. Available from: https://jneonatalsurg.com/ojs/index.php/jns/article/view/295

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