Pulmonary Malformations: Predictors of Neonatal Respiratory Distress and Early Surgery

Authors

  • Sara Costanzo V. Buzzi Children's Hospital, Milano
  • Claudia Flisetti V. Buzzi Children’s Hospital, Milano, and University of Pavia
  • Claudio Vella V. Buzzi Children’s Hospital, Milano
  • Mariangela Rustico V. Buzzi Children’s Hospital, Milano
  • Paola Fontana V. Buzzi Children’s Hospital, Milano
  • Gianluca Lista V. Buzzi Children’s Hospital, Milano
  • Salvatore Zirpoli V. Buzzi Children’s Hospital, Milano
  • Marcello Napolitano V. Buzzi Children’s Hospital, Milano
  • Giovanna Riccipetitoni V. Buzzi Children’s Hospital, Milano

DOI:

https://doi.org/10.21699/jns.v5i3.375

Keywords:

Pulmonary malformations, Prenatal diagnosis, CPAM volume ratio, Fetal therapy, Neonatal resuscitation

Abstract

Objectives: The objective of our study is to retrospectively analyze a single-centre series of antenatally detected pulmonary malformations (PM) and to evaluate their postnatal outcome.

Materials and Methods: We retrospectively reviewed all prenatally diagnosed PM patients referred to our Centre in the period between January 1999 and December 2014. All cases were diagnosed by one of our Maternal-Fetal Specialists by US examination. Congenital pulmonary airway malformation (CPAM) volume ratio (CVR), development of fetal complications, need for fetal therapy, need for neonatal resuscitation and timing of surgery were analyzed.

Results: A total of 70 fetuses were diagnosed with a PM in the period of study. An initial CVR higher than 1.6 was found in 16/70 patients (22.8%); 14/16 developed fetal complications (pConclusion: CVR > 1.6 and the presence of fetal complications can be considered as predictors of respiratory distress at birth and of the need for early surgery. Nevertheless, the vast majority of PM are asymptomatic at birth and only a small group of fetuses require prenatal and postnatal treatment and support.

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Author Biographies

Sara Costanzo, V. Buzzi Children's Hospital, Milano

Department of Pediatric Surgery

Claudia Flisetti, V. Buzzi Children’s Hospital, Milano, and University of Pavia

Department of Pediatric Surgery, V. Buzzi Children’s Hospital, Milano, Italy

Department of Surgery, PhD School of Experimental Medicine, University of Pavia, Italy

Claudio Vella, V. Buzzi Children’s Hospital, Milano

Department of Pediatric Surgery

Mariangela Rustico, V. Buzzi Children’s Hospital, Milano

Maternal-Fetal Department

Paola Fontana, V. Buzzi Children’s Hospital, Milano

Neonatal Intensive Care Unit

Gianluca Lista, V. Buzzi Children’s Hospital, Milano

Neonatal Intensive Care Unit

Salvatore Zirpoli, V. Buzzi Children’s Hospital, Milano

Department of Radiology

Marcello Napolitano, V. Buzzi Children’s Hospital, Milano

Department of Radiology

Giovanna Riccipetitoni, V. Buzzi Children’s Hospital, Milano

Department of Pediatric Surgery

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Published

2016-07-01

How to Cite

1.
Costanzo S, Flisetti C, Vella C, Rustico M, Fontana P, Lista G, Zirpoli S, Napolitano M, Riccipetitoni G. Pulmonary Malformations: Predictors of Neonatal Respiratory Distress and Early Surgery. J Neonatal Surg [Internet]. 2016Jul.1 [cited 2021Feb.28];5(3):27. Available from: https://jneonatalsurg.com/ojs/index.php/jns/article/view/294