An Experience with 31 Cases of Neonatal Appendicitis: A Retrospective Study

Authors

  • Xuxu Huang CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY
  • Xuefei Huang CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY
  • Juma Mfaume Mbugi CHONGQING MEDICAL UNIVERSITY, CHILDREN'S HOSPITAL.
  • Liu Wei CHONGQING MEDICAL UNIVERSITY, CHILDREN'S HOSPITAL.
  • Hua Ziyu CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY,CHONGQING-CHINA MINISTRY OF EDUCATION KEY LABORATORY OF CHILD DEVELOPMENT AND DISORDERS, CHONGQING-CHINA. CHONGQING INFORMATIONAL SCIENCE AND TECHNOLOGY COOPERATION CENTER FOR CHILD DEVELOPMENT AND DISORDERS,CHONGQING -CHINA.
  • Hu Ya CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY
  • Zhao Qianqian CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY
  • Yue Weihong CHILDEREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY
  • Wei Hong CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

Keywords:

Acute appendicitis, Neonatal appendicitis, Necrotizing enterocolitis

Abstract

Background: Neonatal appendicitis (NA) is rarely diagnosed due to lack of specific symptoms and signs. The aim of this study is to share our experience with NA.

Methods: We performed a retrospective data review from electronic medical records of patients admitted at Children’s Hospital of Chongqing Medical University (CHCMU) with the clinical diagnosis of NA from October 2001 to July 2018.

Results: Of 31 neonates, male neonates (n=20) accounted for 64.5%. Abdominal distension and anorexia were the most common clinical features (61.3%, n=19). Neonates with elevated C- reactive protein (CRP) accounted for 92.6% (n=25) where as 51.6% (n=16) had normal white blood cell count (WBC). Of 29 neonates who underwent surgery, 69% (n=20) had perforated appendicitis.

Conclusion: Neonatal appendicitis lacks specific clinical features, and early diagnosis is difficult. Clinicians need to have high index of suspicion when attending neonates with features of abdominal sepsis.

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Author Biographies

Xuxu Huang, CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

DEPARTMENT OF NEONATOLOGY

RESIDENT DOCTOR.

Xuefei Huang, CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

NEONATOLOGY DEPARTMENT

RESIDENT DOCTOR.

Juma Mfaume Mbugi, CHONGQING MEDICAL UNIVERSITY, CHILDREN'S HOSPITAL.

CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

DEPARTMENT OF NEONATOLOGY

 

Liu Wei, CHONGQING MEDICAL UNIVERSITY, CHILDREN'S HOSPITAL.

Department of Surgical Gastroenterology, Children’s Hospital of Chongqing Medical University,

Hua Ziyu, CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY,CHONGQING-CHINA MINISTRY OF EDUCATION KEY LABORATORY OF CHILD DEVELOPMENT AND DISORDERS, CHONGQING-CHINA. CHONGQING INFORMATIONAL SCIENCE AND TECHNOLOGY COOPERATION CENTER FOR CHILD DEVELOPMENT AND DISORDERS,CHONGQING -CHINA.

PROFESSOR, DEPARTMENT OF NEONATOLOGY

Hu Ya, CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

DEPARTMENT OF NEONATOLOGY

Zhao Qianqian, CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

DEPARTMENT OF NEONATOLOGY

Yue Weihong, CHILDEREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

DEPARTMENT OF NEONATOLOGY

Wei Hong, CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

PROFESSOR, DEPARTMENT OF NEONATOLOGY

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Published

2019-12-27

How to Cite

1.
Huang X, Huang X, Mbugi JM, Wei L, Ziyu H, Ya H, Qianqian Z, Weihong Y, Hong W. An Experience with 31 Cases of Neonatal Appendicitis: A Retrospective Study. J Neonatal Surg [Internet]. 2019Dec.27 [cited 2021Mar.1];8(3):21. Available from: https://jneonatalsurg.com/ojs/index.php/jns/article/view/241