Intestinal Strictures Post-Necrotising Enterocolitis: Clinical Profile and Risk Factors

Authors

  • Nilkant Phad Grace Centre for Newborn Care The Children's Hospital at Westmead Westmead NSW 2145 Australia
  • Amit Trivedi Grace Centre for Newborn Care The Children's Hospital at Westmead Westmead NSW 2145 Australia
  • David Todd
  • Anil Lakkundi

DOI:

https://doi.org/10.47338/jns.v3.134

Keywords:

Necrotising enterocolitis, Intestinal strictures

Abstract

Background: Intestinal stricture is an important complication of necrotising enterocolitis (NEC). We aimed to describe clinical profile and identify the risk factors for post-NEC intestinal strictures.

Method: A retrospective study of infants with NEC over 10 year period.

Results: Of the 61 infants with NEC, 18 (29.5%) developed intestinal strictures. Leucocytosis and longer length of bowel resection during acute stage of NEC was associated with a later diagnosis of intestinal stricture. Infants with NEC who did not develop stricture had non-specific intestinal dilatation on abdominal x-ray during acute NEC. Intestinal strictures were diagnosed at a median interval of 34 days after NEC. Majority of strictures (67%) occurred in the colon. A significant proportion (77%) of infants with intestinal stricture had associated co-morbidities. No mortality occurred in infants with intestinal strictures.

Conclusion: The incidence of post-NEC intestinal stricture is high but development of stricture is difficult to predict. Leucocytosis during NEC and length of bowel resected at surgery may be associated with development of post-NEC intestinal stricture. A substantial number of infants with post-NEC intestinal stricture fail to thrive, have co-morbidities and need prolonged hospitalisation.

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Published

2014-10-10

How to Cite

1.
Phad N, Trivedi A, Todd D, Lakkundi A. Intestinal Strictures Post-Necrotising Enterocolitis: Clinical Profile and Risk Factors. J Neonatal Surg [Internet]. 2014Oct.10 [cited 2021Feb.25];3(4):J Neonat Surg. 2014; 3(4):44. Available from: https://jneonatalsurg.com/ojs/index.php/jns/article/view/134